Ciba Foundation Symposium - Metabolic Breakdown of Steroids

Chapter 1 The Metabolism of C19 Steroids by means of person Tissues (pages 236–243): Leo T. Samuels
Chapter 2 In vivo Metabolism of C19 Steroids (pages 244–250): Frank Ungar and Ralph I. Dorfman
Chapter three Is Dehydroisoandrosterone remoted from Urine Extracts an unique 17?Ketosteroid or a made of Chemical Degradation? (pages 251–273): E. Dingemanse
Chapter four The impact of Androgens at the Urinary Excretion of Steroid Alcohols and ?strogens (pages 274–285): Lewis L. Engel, Marion Lance, Gladys Ekman, Katherine H. Spaulding, Priscilla Carter and Ira T. Nathanson
Chapter five Excretion of Steroids in a Case of Interstitial cellphone Tumour of the Testis (pages 286–290): Eleanor H. Venning
Chapter 6 Metabolism of impartial C21 and C19 Steroids (pages 291–308): Ralph I. Dorfman
Chapter 7 Progesterone Metabolism—A evaluate (pages 309–326): William H. Pearlman
Chapter eight The Metabolism of Progesterone in Goats (pages 327–328): R. J. Boscott
Chapter nine The Separation of Urinary Cortical Steroids (pages 329–333): R. J. Boscott
Chapter 10 The middleman Metabolism of Progesterone in Human topics (pages 334–346): Ian F. Sommerville
Chapter eleven The Metabolism of Progesterone and similar Compounds (pages 347–353): Ralph I. Dorfman, Frank Ungar, Paul Wgnos, Robert M. Stecher and Norman Shumway
Chapter 12 Metabolic experiences on Orally Administered Progesterone (pages 354–358): Eleanor H. Venning
Chapter thirteen Blood Progesterone in being pregnant (pages 359–365): C. J. O. R. Morris
Chapter 14 On attainable Relationships among the Metabolic Breakdown of Progesterone and its organic job (pages 366–374): H. S. Guterman
Chapter 15 11?Oxygenating Enzyme method (pages 375–380): Ralph I. Dorfman and Mika Hayano
Chapter sixteen The Metabolism of Steroid Hormones in people (pages 381–417): okay. Dobriner and S. Lieberman
Chapter 17 The impact of Corticosteroids on Carbohydrate and Electrolyte Metabolism in vitro (pages 418–422): F. Verzar
Chapter 18 Chairman's ultimate comments (pages 423–424): R. okay. Callow

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Additional resources for Ciba Foundation Symposium - Metabolic Breakdown of Steroids (Book II on Colloquia on Endocrinology), Volume II

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I I! i! 1: ii i! : i! i ;i 1: . 2. 17-Ketosteroid chromatogram. Addition of various amounts of dehydroisoandrosterone to extract of urine of normalman. DEHYDRO~SOANDROSTERONE IN URINE 255 leaves the column a t the same place. One-half, three and four milligrams of deh ydroisoandrosterone were eluted in succession. The 17-ketosteroid always left the column at the same place. Addition of the non-ketonic fraction of urine extract was also without effect on the place of elution, providing that the weight of the 17-ketosteroid was smaller than 5 mg.

DINGEMANSE 270 aetiocholanolone we have the solution to Mason’s problem. (Fig. 12). Finally, is dehydroisoandrosterone also an artifact in the urine of normal subjects? The answer is this: when the urine of normal subjects is hydrolysed first at neutral and then I t E 40 9 8 1 b of 3 Lays Era. 12: I%Ketosteroid excretion after administration of dehydnnaoandmeterone acetate and of i-androstanolone to a n o d man. A, C, E=contds. B =Administration of 800 mg. dehydmkoandrosteroneacetate in 72 hr. C=Administration of 225 mg.

P. and that of its acetate. When the chromatographic analysis was included in the purification (Jy3-4 r e e m tsmp. 9. Formation of dehydroisoandrosterone fmm 17-ketosteroid I1 (i-androstanolone). procedure it was found possible to isolate without any difficulty very small quantities (approx. ) of the material in a very pure condition. Furthermore, the reaction products were already identifiable by their positions in the chromatogram. We were thus obliged to assume that under the influence of hydrochloric acid the reactions shown in Fig.

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